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Pregnancy or Planning Pregnancy No safety data in pregnancy Must stop at least 2 months before attempting conception 4

People with chronic kidney disease or frailty may have specific protein requirements and should discuss individual targets with a registered dietitian

Tirzepatide is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that you inject once weekly under the skin

Clinical trial data from the NEJM Phase 2 study showed that gastrointestinal events were predominantly mild to moderate, occurred primarily during dose escalation, and were partially mitigated by starting at 2mg rather than 4mg